human artificial chromosome การใช้

• In 2011, researchers formed a human artificial chromosome by truncating chromosome 14.
• Germline engineering and even the engineering of human artificial chromosomes ( which presently allow increased reliability ) are presently being done in animals.
• Artificial chromosomes, even human artificial chromosomes, have already been created and patented, the scientists reported, and companies have sprung up to exploit the technology.
• In 2010, a refined human artificial chromosome called 21HAC was reported . 21HAC is based on a stripped copy of human chromosome 21, producing a chromosome 5 Mb in length.
• Truncation of chromosome 21 resulted in a human artificial chromosome that is mitotically stable . 21HAC was also able to be transferred into cells from a variety of species ( mice, chickens, humans ).
• Yeast artificial chromosomes and bacterial artificial chromosomes were created before human artificial chromosomes, which first appeared in vectors, as a tool for elucidating human chromosome function, and as a method for actively annotating the human genome.
• His current research interests include genome sciences and their broad implications for medicine and society, human chromosome structure and function, X-inactivation and mechanisms of gene silencing, and the first reported development of human artificial chromosomes for studies of gene transfer and functional genomics.